Current Prospects of Medicinal Plants and Their Constituents for Treatment of Liver Diseases

Abstract

Nature has always been a remarkable source of therapeutic substances, offering a wide range of therapeutic plants that produce advantageous phytochemicals. Liver illness is a severe condition, and the situation is made worse by the absence of specific treatment plans. The treatments for liver diseases that are now available are inappropriate, and systemic toxicity prevents their long-term usage. Since medicinal herbs seem to have a reduced toxicity level, they have been utilized historically for ages to treat liver problems. Numerous therapeutic plants and their phytoconstituents have been shown to have strong hepatoprotective properties with no systemic side effects, which may restrict their long-term application. Since medicinal herbs seem to have a reduced toxicity level, they have been utilized historically for ages to treat liver problems. Numerous therapeutic plants and their phytoconstituents have been shown to have strong hepatoprotective properties with no systemic side effects, which may restrict their long-term application. Research has shown that the primary mechanism by which phytoconstituents reduce various disease pathways is through their antioxidant qualities, which include boosting the cells' antioxidant defense system, scavenging free radicals, lowering lipid peroxidation, enhancing their anti-inflammatory potential, and further preventing hepatic cell damage. In conclusion, this study highlights the significance of additional research to examine the effectiveness and safety of these natural medicines for a variety of liver illnesses by compiling the knowledge on medicinal plants and their possibly hepatoprotective bioactive phytoconstituents.