The Epidemiology of Alzheimer’s Disease and It’s Phyto-Therapeutic Approaches

Abstract

The most prevalent kind of dementia, Alzheimer's disease (AD), provides a stunning illustration of the link between higher-order cognitive deficits and neurophysiological anomalies. Research on the pathophysiology and etiology of AD has revealed an incredibly complex set of genetic and molecular mechanisms for the disease's progression since the disease was first described in 1906. AD is characterized by much more than just the neuropathological hallmarks of beta-amyloid (Aβ) plaques and neurofibrillary tangles (NFTs). Results linking the neurodegeneration seen in AD to the disease's clinical manifestation and course of therapy are included in this review, with a focus on the pathophysiology of the disease. Herbal-based therapeutic agents have been shown to have long-lasting effects that could safeguard the health of the nervous system, reduce inflammatory responses, enhance cognitive function, provide anti-aging effects in the natural ageing process, and reduce dementia sequelae. Herbal based therapeutic agents offer many benefits and can potentially be used as new generation therapeutics or complementary agents with high compliance, low side effects, and low cost compared to traditional pharmaceutical agents in the battle against AD.