Investigating the Therapeutic Effects of Gold Nanoparticles in Neurological Diseases

Abstract

Gold nanoparticles (GNPs) are emerging as a promising tool in the treatment of neurological diseases due to their unique physicochemical properties and multifunctionality. This review explores the therapeutic applications of GNPs in addressing the complex pathologies of Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and stroke and traumatic brain injury. GNPs exhibit anti-inflammatory and antioxidant effects, protect neurons, and enhance drug delivery to the central nervous system (CNS). Advances in GNP design, including next-generation and multifunctional nanoparticles, are discussed, highlighting their potential to improve targeting and efficacy. Personalized nanomedicine approaches offer tailored treatments based on individual patient profiles, enhancing therapeutic outcomes. Additionally, the integration of GNPs with conventional therapies can produce synergistic effects, amplifying treatment efficacy. This review underscores the potential of GNPs to revolutionize the management of neurological diseases, paving the way for precision medicine and improved patient care.