Immunological Biomarker of Leishmania Donovani

Abstract

Leishmania donovani are major disease causes and humans are the main reservoir. In addition to Leishmania infantum, Leishmania archibaladi, and Leishmania chgasi. infection, such as cytokines IL-2, IL-10, IL-12, and TGF-β, was detected using ELISA technology. The results showed a significant increase in the concentration of these cytokines in the test group (131.58 ± 15.92, 335.68 ± 15.57, 823.62 ± 98.75, 341.16 ± 15.19), respectively, for patients infected with visceral leishmaniasis compared to the healthy control group