Dynamics of Local Immunity of the Oral Cavity at the Stages of Treatment

Abstract

: Inflammatory periodontal diseases are associated with local and systemic increases in the levels of proinflammatory cytokines, such as tumor necrosis factor a, IL-6 and prostaglandins, and lead to tissue destruction through the participation of matrix metalloproteinases. Stress disrupts the balance between pro-inflammatory and anti-inflammatory responses. The article describes the dynamics of sIgA, salivary flow rate and sIgA concentration in saliva in teachers with chronic work stress against the background of complex treatment. 131 teachers of secondary schools and teachers of SamSMU with different periods of work experience took part in the study. Thus, based on the data presented above, we can conclude that measures to correct stress among teachers are recommended to be carried out every 6 months. This study presents new data on the immune functioning of the oral cavity in individuals with occupational stress among university and secondary school teachers. It demonstrates the relationship between perceived stress with salivary secretion and SIgA levels.