Development Evaluation and Estimation of Phytobioactive Antifungal Compounds for the Treatment of Atopic Dermatitis

Abstract

One of the most prevalent chronic inflammatory skin illnesses, atopic dermatitis (AD) is brought on by a variety of reasons, such as infections, host immunological responses, genetics, skin barrier abnormalities, allergen sensitivity, and environmental influences. Patients with AD frequently have bacterial and viral infections in their eczematous lesions, which obviously exacerbates the symptoms. Despite reports indicating that some dermatophytes, Candida, and Malassezia can impact AD symptoms, research on fungal infections in AD is very scarce. The current study created and assessed an antifungal cream that contained hydro-alcoholic extracts of Tecoma stans leaves. Chlorogenic acid, a phytobioactive antifungal component, was also evaluated in the produced formulation and extract.