In Vitro Antidiabetic and Anti- Inflammatory Analysis of Rhizome Extract of Hedychium Flavescens

Abstract

The principle of this study was to assess the potential anti-inflammatory and anti-diabetic properties of Hedychiumflavescens. The anti-diabetic  activity was determined using the α-amylase inhibitory assay with the DNSA method, while the anti-inflammatory activity was evaluated using a modified version of the method developed by Mizushima et al. In the examination of the antidiabetic effects, the acetone extract of Hedychiumflavescens rhizome demonstrated an IC50 value of 50.25 μg/ml, indicating higher activity compared to the standard Acarbose. However, the acetone rhizome extract exhibited relatively lower inhibition in terms of anti-inflammatory activity, with an IC50 value of 82.26 μg/ml compared to the standard.