Anthelmentic Activity of Syzygium Aromatica Compare with Marketed Formulation of Albendazole Suspension

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Kiran C. Mahajan
AdityaR.Suryawanshi
Santosh B. Kallur
Urmila V. Anande
Shubhangi T. Chakave
Mamata G. Vishe
Yogesh V. Marewad
Maya K. Pokharkar

Abstract

The anthelmintic drugs show their effects on the human body and their regular activities by causing helminthiasis which is a very severe parasitic disease. The paralysis and death time of earthworms after administering doses were determined. The result of anthelmintic activity of earthworms showed that the earthworms had taken less time for paralysis and less time for death. It can be concluded that earthworms can be used successfully for the anthelmintic activity study as it is easy, prominent, an adaptable to laboratory conditions. Evaluation of anthelmintic activity of any drug when carried out in laboratory conditions by using the isolated worms from nature cannot be adaptable with artificial laboratory conditions. The present anthelmintic activity study reveals a new methodology with earth worms cultured in laboratory conditions. We studied the anthelmintic activities of anSyzygiumaromaticumcompare with marketed formulation of albendazolesuspension. The result showed that the earthworms had taken less time for paralysis and death when usedSyzygiumaromaticumbud powder extract. This novel dosage form might be a promising dosage form in the prevention of worm infections for pediatric patients.

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